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1.发明公开TRANSCRIPTOMIC BIOMARKERS, METHOD FOR DETERMINATION THEREOF AND USE OF TRNASCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT OF DEVELOPING POST-INFRACTION HEART FAILURE 审中-公开转录生物标记物的方法来确定哪些和心衰的发展评估个体风险转录组生物标记物的使用后梗死
公开(公告)号：EP3105350A2
公开(公告)日：2016-12-21
申请号：EP15712187.2
申请日：2015-02-12
申请人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Warszawski Uniwersytet Medyczny , Uniwersytet Medyczny W Bia Ymstoku
发明人： BURZYNSKA, Beata , GÓRA, Monika , MACIEJAK, Agata , TULACZ, Dorota , KILISZEK, Marek , MICHALAK, Marcin , OPOLSKI, Grzegorz , MATLAK, Krzysztof , DOBRZYCKI, Slawomir
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/158
摘要： The invention relates to biomarkers for individual risk assessment of the development of post-infarction heart failure, the method of determining the markers in samples of biological material collected from a patient. Further, the invention relates to a use of the biomarkers in the diagnosis (expression level of the gene) that correlate with the developing post-infarction heart failure, and enable prevention of heart disease based on a genetic marker and a method for predicting the risk of developing a heart failure for post-infarction patients. Also a method for optimizing the treatment of cardiac patients with the use of the means of the invention is disclosed.
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公开(公告)号：EP3105350B1
公开(公告)日：2019-04-10
申请号：EP15712187.2
申请日：2015-02-12
申请人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Warszawski Uniwersytet Medyczny , Uniwersytet Medyczny W Bialymstoku
发明人： BURZYNSKA, Beata , GÓRA, Monika , MACIEJAK, Agata , TULACZ, Dorota , KILISZEK, Marek , MICHALAK, Marcin , OPOLSKI, Grzegorz , MATLAK, Krzysztof , DOBRZYCKI, Slawomir
IPC分类号： C12Q1/6883
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