发明公开
EP3110971A2 T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF
审中-公开
T-ZELLEN-BALANCE-GENEXPRESSSION，MATERIALZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG DAVON
- 专利标题： T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF
- 专利标题（中）： T-ZELLEN-BALANCE-GENEXPRESSSION，MATERIALZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG DAVON
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申请号： EP15709048.1申请日： 2015-02-26
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公开(公告)号： EP3110971A2公开(公告)日： 2017-01-04
- 发明人: KUCHROO, Vijay , REGEV, Aviv , GAUBLOMME, Jellert , LEE, Youjin , SHALEK, Alexander, K. , WANG, Chao , YOSEF, Nir , PARK, Hongkun
- 申请人： The Broad Institute Inc. , The Brigham and Women's Hospital, Inc. , President and Fellows of Harvard College , Massachusetts Institute of Technology
- 申请人地址： 415 Main Street Cambridge, MA 02142 US
- 专利权人： The Broad Institute Inc.,The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- 当前专利权人： The Broad Institute Inc.,The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- 当前专利权人地址： 415 Main Street Cambridge, MA 02142 US
- 代理机构： V.O.
- 优先权： US201461945641P 20140227
- 国际公布： WO2015130968 20150903
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.
公开/授权文献
- EP3110971B1 T CELL BALANCE GENE EXPRESSION AND METHODS OF USE THEREOF 公开/授权日：2019-05-08
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