发明公开
EP3116874A1 HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL
有权
麻黄碱HITAHYDRODIAZEPINCHINOLINE MIT EINEM SUBSTITUIERTEN ALKYLRADIKAL
- 专利标题： HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL
- 专利标题（中）： 麻黄碱HITAHYDRODIAZEPINCHINOLINE MIT EINEM SUBSTITUIERTEN ALKYLRADIKAL
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申请号： EP15711464.6申请日： 2015-03-13
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公开(公告)号： EP3116874A1公开(公告)日： 2017-01-18
- 发明人: BACKFISCH, Gisela , BAKKER, Margaretha Henrica Maria , BLAICH, Günter , BRAJE, Wilfried , DRESCHER, Karla , ERHARD, Thomas , HAUPT, Andreas , LAKICS, Viktor , REINGRUBER, Anna , MACK, Helmut , PETER, Raimund , RELO, Ana Lucia , SMYTH, Lynette
- 申请人： AbbVie Deutschland GmbH & Co. KG
- 申请人地址： Mainzer Strasse 81 65189 Wiesbaden DE
- 专利权人： AbbVie Deutschland GmbH & Co. KG
- 当前专利权人： AbbVie Deutschland GmbH & Co. KG
- 当前专利权人地址： Mainzer Strasse 81 65189 Wiesbaden DE
- 代理机构： Reitstötter Kinzebach
- 优先权： US201461953337P 20140314
- 国际公布： WO2015136091 20150917
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/5513 ; A61P25/00
摘要：
The present invention relates to tricyclic hexahydrodiazepinoquinolines carrying a substituted alkyl radical, to a method for producing them, to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT2C receptor, their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT2C receptor, to a method for preventing or treating conditions and disorders which respond to the modulation of 5-HT2C receptor, and processes for preparing such compounds and compositions.
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