发明公开
EP3124016A1 ANTIPSORIATIC EMULSION COMPOSITION COMPRISING CEFAZOLIN
审中-公开
乳液麻醉CEFAZOLIN GEGEN PSORIASIS
- 专利标题： ANTIPSORIATIC EMULSION COMPOSITION COMPRISING CEFAZOLIN
- 专利标题（中）： 乳液麻醉CEFAZOLIN GEGEN PSORIASIS
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申请号： EP15460037.3申请日： 2015-07-31
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公开(公告)号： EP3124016A1公开(公告)日： 2017-02-01
- 发明人: Zegrocka-Stendel, Oliwia , Huszcza, Grzegorz , Pesta, Edyta , Smedra, Katarzyna , Koziak, Katarzyna
- 申请人： Warszawski Uniwersytet Medyczny , INSTYTUT FARMACEUTYCZNY
- 申请人地址： Ul. Zwirki i Wigury 61 02-091 Warszawa PL
- 专利权人： Warszawski Uniwersytet Medyczny,INSTYTUT FARMACEUTYCZNY
- 当前专利权人： Warszawski Uniwersytet Medyczny,INSTYTUT FARMACEUTYCZNY
- 当前专利权人地址： Ul. Zwirki i Wigury 61 02-091 Warszawa PL
- 代理机构： Lazewski, Marek
- 主分类号： A61K9/107
- IPC分类号： A61K9/107 ; A61K9/113 ; A61K47/02 ; A61K47/06 ; A61K47/08 ; A61K47/10 ; A61K47/18 ; A61K31/546
摘要：
The present invention relates to the antipsoriatic emulsion composition, especially in the form of a cream, comprising an effective therapeutic dose of cefazolin, the ingredients of the oil phase and the ingredients of the water phase, characterized by that
(i) the ingredients of the oil phase include:
- liquid paraffin or white petrolatum,
- polyoxyethylene stearyl ether (21), and
- cetostearyl alcohol;
(ii) the ingredients of the oil phase include a buffer solution to maintain the pH value of the initial composition from 5 to 9, preferably in the range 6 - 8,
(iii) optionally, comprising an additional amphiphilic nonionic emulsifier, and other soluble/water miscible excipients,
wherein water content accounts for 50 to 80% by weight of the composition.
(i) the ingredients of the oil phase include:
- liquid paraffin or white petrolatum,
- polyoxyethylene stearyl ether (21), and
- cetostearyl alcohol;
(ii) the ingredients of the oil phase include a buffer solution to maintain the pH value of the initial composition from 5 to 9, preferably in the range 6 - 8,
(iii) optionally, comprising an additional amphiphilic nonionic emulsifier, and other soluble/water miscible excipients,
wherein water content accounts for 50 to 80% by weight of the composition.
公开/授权文献
- EP3124016B1 ANTIPSORIATIC EMULSION COMPOSITION COMPRISING CEFAZOLIN 公开/授权日：2019-09-04
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