发明公开
- 专利标题: MICRONIZED WHARTON'S JELLY
- 专利标题(中): MIKRONISIERTE WHARTON-SULZE
-
申请号: EP15796851.2申请日: 2015-05-21
-
公开(公告)号: EP3146039A1公开(公告)日: 2017-03-29
- 发明人: SPENCER, Randall , SITH, Somaly
- 申请人: MiMedx Group, Inc.
- 申请人地址: 1775 West Oak Commons Ct. NE Marietta, GA 30062 US
- 专利权人: MiMedx Group, Inc.
- 当前专利权人: MiMedx Group, Inc.
- 当前专利权人地址: 1775 West Oak Commons Ct. NE Marietta, GA 30062 US
- 代理机构: Gibson, Mark
- 优先权: US201462001600P 20140521
- 国际公布: WO2015179711 20151126
- 主分类号: C12N5/00
- IPC分类号: C12N5/00
摘要:
The present invention provides compositions and formulations of micronized Wharton's jelly having a controlled viscosity such that when delivered to the injured region of a subject, it remains substantially localized with little or no migration out of the injured region for the repair and/or regeneration thereof. Micronized Wharton's Jelly can be suspended in a pharmaceutically acceptable aqueous carrier, such as saline, sterile water, or any suitable buffer, to form a suspension or a gelatinous gel composition, or it can be in the form of a paste, suitable for delivery into the space adjacent the articular surface cartilage injured region of a subject. The micronized Wharton's jelly when employed at sufficient concentrations can be hydrated into a gel or paste and administered topically, or it can be injected into the body through the use of a needle and syringe. Accordingly, micronized Wharton's Jelly, compositions, or formulations thereof, can be delivered in a manner that is more convenient than Wharton's jelly that has not been micronized in accordance with the present invention.
信息查询