发明公开
EP3149212A1 ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES
审中-公开
ELEKTROCHEMISCHE VERFAHREN UND VERBINDUNGEN ZUR DETEKTION VON ENZYMEN
- 专利标题: ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES
- 专利标题(中): ELEKTROCHEMISCHE VERFAHREN UND VERBINDUNGEN ZUR DETEKTION VON ENZYMEN
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申请号: EP15799039.1申请日: 2015-06-01
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公开(公告)号: EP3149212A1公开(公告)日: 2017-04-05
- 发明人: IYER, Suri Saranathan , DHAWANE, Abasaheb , HE, Yun , ZHANG, Xiaohu , DINH, Hieu , VASIREDDI, Mugdha , SWEENEY, Joyce
- 申请人: Georgia State University Research Foundation, Inc.
- 申请人地址: 30 Courtland Street Suite 326 Atlanta, GA 30303 US
- 专利权人: Georgia State University Research Foundation, Inc.
- 当前专利权人: Georgia State University Research Foundation, Inc.
- 当前专利权人地址: 30 Courtland Street Suite 326 Atlanta, GA 30303 US
- 代理机构: Gassner, Birgitta
- 优先权: US201462005407P 20140530; US201462091205P 20141212
- 国际公布: WO2015184442 20151203
- 主分类号: C12Q1/70
- IPC分类号: C12Q1/70 ; G01N27/327
摘要:
Disclosed are compositions and methods for the electrochemical detection of enzymes, such as enzymes that are indicative of disease, disorders, or pathogens, such as viruses, bacteria, and fungi, or other disorders. These methods can be used in point-of-care diagnostic assays for the detection of disease, disorder, or pathogen (e.g., to identify the strain of pathogen infecting a patient in a healthcare setting). The electrochemical methods described herein can also be used to assess the susceptibility of a pathogen to an antipathogen drug. Also provided are probes suitable for use in conjunction with the methods described herein.
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