发明公开
- 专利标题： METHODS OF TREATING CANCER AND PREVENTING CANCER DRUG RESISTANCE
- 专利标题（中）： 治疗癌症和预防癌症药物抗性的方法
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申请号： EP15810899.3申请日： 2015-06-23
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公开(公告)号： EP3157524A1公开(公告)日： 2017-04-26
- 发明人: CLASSON, Marie , GULER, Gulfem Dilek , PITTI, Robert , STEPHAN, Jean-Philippe , TINDELL, Charles Albert
- 申请人： Genentech, Inc.
- 申请人地址： 1 DNA Way South San Francisco, CA 94080-4990 US
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： 1 DNA Way South San Francisco, CA 94080-4990 US
- 代理机构： Bailey, Sam Rogerson
- 优先权： US201462015932P 20140623
- 国际公布： WO2015200329 20151230
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; A61K31/404 ; A61P35/00
摘要：
Provided herein are methods of using antagonists of G9a, for example, for treating cancer and/or preventing drug resistance in an individual. For example, a method of treating cancer in an individual comprising administering to the individual an antagonist of G9a alone or in combination with a cancer therapy agent is provided. In some embodiments, the antagonist of G9a increases the period of cancer sensitivity and/or delays development of cancer resistance.
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