发明公开
- 专利标题： GLUTAMINASE INHIBITOR THERAPY
- 专利标题（中）： 谷氨酰胺酶，HEMMERTHERAPIE
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申请号： EP15814655.5申请日： 2015-07-03
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公开(公告)号： EP3164195A1公开(公告)日： 2017-05-10
- 发明人: HEFFERNAN, Timothy , TONIATTI, Carlo , KOVACS, Jeffrey , GIULIANI, Virginia , SPENCER, Nakia , DI FRANCESCO, Maria Emilia , BRISTOW, Christopher A.
- 申请人： Board of Regents, The University of Texas System
- 申请人地址： 201 West 7th Street Austin, TX 78701 US
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： 201 West 7th Street Austin, TX 78701 US
- 代理机构： Boult Wade Tennant
- 优先权： US201462020731P 20140703; US201462020539P 20140703; US201462020519P 20140703; US201462020524P 20140703; US201562187160P 20150630; US201514791186 20150702; US201514791206 20150702
- 国际公布： WO2016004418 20160107
- 主分类号： A61P39/06
- IPC分类号： A61P39/06
摘要：
Disclosed herein are methods of treating a subject having an altered NRF2/KEAP1 pathway, and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject.
公开/授权文献
- EP3164195B1 GLUTAMINASE INHIBITOR THERAPY 公开/授权日：2022-06-15
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