- 专利标题： PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS JANUS KINASE INHIBITOR
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申请号： EP16197502.4申请日： 2006-12-12
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公开(公告)号： EP3184526B1公开(公告)日： 2018-10-03
- 发明人: RODGERS, James D. , SHEPARD, Stacey , MADUSKUIE, Thomas P. , WANG, Haisheng , FALAHATPISHEH, Nikoo , RAFALSKI, Maria , ARVANITIS, Argyrios G. , STORACE, Louis , JALLURI, Ravi Kumar , FRIDMAN, Jordan S. , VADDI, Krishna
- 申请人： Incyte Holdings Corporation
- 申请人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 专利权人： Incyte Holdings Corporation
- 当前专利权人： Incyte Holdings Corporation
- 当前专利权人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US749905P 20051213; US810231P 20060602; US850625P 20061010; US856872P 20061103; US859404P 20061116
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; A61K31/395 ; A61P17/00 ; A61P35/00 ; A61P37/00
摘要：
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines (I) and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
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