发明公开
EP3189134A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR GENERATING INNER EAR HAIR CELLS FOR TREATMENT OF HEARING LOSS
审中-公开
用于产生听力损失的用于产生内耳毛细胞的组合物，系统和方法
- 专利标题： COMPOSITIONS, SYSTEMS, AND METHODS FOR GENERATING INNER EAR HAIR CELLS FOR TREATMENT OF HEARING LOSS
- 专利标题（中）： 用于产生听力损失的用于产生内耳毛细胞的组合物，系统和方法
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申请号： EP15778076.8申请日： 2015-09-03
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公开(公告)号： EP3189134A1公开(公告)日： 2017-07-12
- 发明人: KARP, Jeffrey M. , LANGER, Robert S. , YIN, Xiaolei , JOSHI, Nitin
- 申请人： The Brigham and Women's Hospital, Inc. , Massachusetts Institute of Technology
- 申请人地址： 75 Francis Street Boston, MA 02115 US
- 专利权人： The Brigham and Women's Hospital, Inc.,Massachusetts Institute of Technology
- 当前专利权人： The Brigham and Women's Hospital, Inc.,Massachusetts Institute of Technology
- 当前专利权人地址： 75 Francis Street Boston, MA 02115 US
- 代理机构： Crease, Devanand John
- 优先权： US201462045506P 20140903; US201462051003P 20140916
- 国际公布： WO2016037016 20160310
- 主分类号： C12N5/0793
- IPC分类号： C12N5/0793 ; A61K35/12
摘要：
Method and compositions for inducing the self-renewal of stem/progenitor supporting cells comprised by a cochlear cell population, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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