发明公开
EP3191600A1 LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE
审中-公开
LUCIFERASE序列利用红外发射基质来产生增强的发光
- 专利标题： LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE
- 专利标题（中）： LUCIFERASE序列利用红外发射基质来产生增强的发光
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申请号： EP15767679.2申请日： 2015-09-11
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公开(公告)号： EP3191600A1公开(公告)日： 2017-07-19
- 发明人: ENCELL, Lance, P. , HALL, Mary, P. , WOOD, Keith, V. , WOOD, Monika, G.
- 申请人： Promega Corporation
- 申请人地址： 2800 Woods Hollow Road Madison, WI 53711-5399 US
- 专利权人： Promega Corporation
- 当前专利权人： Promega Corporation
- 当前专利权人地址： 2800 Woods Hollow Road Madison, WI 53711-5399 US
- 代理机构： Hoffmann Eitle
- 优先权： US201462049150P 20140911
- 国际公布： WO2016040788 20160317
- 主分类号： C12Q1/66
- IPC分类号： C12Q1/66 ; C12N9/02 ; C12N15/53
摘要：
Provided herein are isolated polynucleotide encoding modified click beetle luciferase polypeptides that have enhanced luminescence and longer wavelength near-infrared signals. The disclosure also relates to near-infrared bioluminescence systems that include said modified click beetle luciferase polypeptides and novel luciferin derivatives, as well as methods of using said modified click beetle luciferase polypeptides and bioluminescence systems.
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