发明公开
- 专利标题： MACROCYCLIC RIP2 KINASE INHIBITORS
- 专利标题（中）： MACROCYCLIC RIP2激酶抑制剂
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申请号： EP15766800.5申请日： 2015-09-17
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公开(公告)号： EP3194407A1公开(公告)日： 2017-07-26
- 发明人: HOFLACK, Jan , BLOM, Petra , BENDERITTER, Pascal
- 申请人： Oncodesign S.A.
- 申请人地址： 20 Rue Jean Mazen B.P. 27 627 21076 Dijon Cedex FR
- 专利权人： Oncodesign S.A.
- 当前专利权人： Oncodesign S.A.
- 当前专利权人地址： 20 Rue Jean Mazen B.P. 27 627 21076 Dijon Cedex FR
- 代理机构： LC Patents
- 优先权： EP14185130 20140917
- 国际公布： WO2016042087 20160324
- 主分类号： C07D498/22
- IPC分类号： C07D498/22 ; A61K31/529 ; A61P29/00
摘要：
The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of RIP2 and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of RIP2-kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent.
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