发明公开
- 专利标题： HETEROCYCLYLAMINES AS PI3K INHIBITORS
- 专利标题（中）： 杂环胺用作PI3K抑制剂
-
申请号： EP16199883.6申请日： 2012-08-31
-
公开(公告)号： EP3196202A1公开(公告)日： 2017-07-26
- 发明人: LI,, Yun-Long , YAO,, Wenqing , COMBS,, Andrew, P. , YUE,, Eddy, W. , MEI,, Song , ZHU, Wenyu , GLENN,, Joseph , MADUSKUIE,, Thomas, P., Jr. , SPARKS,, Richard, B. , DOUTY,, Brent , HE,, Chunhong
- 申请人： Incyte Holdings Corporation
- 申请人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 专利权人： Incyte Holdings Corporation
- 当前专利权人： Incyte Holdings Corporation
- 当前专利权人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US201161530866P 20110902; US201261594882P 20120203; US201261677445P 20120730
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P29/00 ; A61P27/00 ; A61P19/00 ; A61P1/00 ; A61P17/00
摘要：
The present invention provides heterocyclylamine derivatives of Formula I:
wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
公开/授权文献
- EP3196202B1 HETEROCYCLYLAMINES AS PI3K INHIBITORS 公开/授权日：2019-02-27
信息查询
