发明公开
- 专利标题： DYSLIPIDEMIA THERAPEUTIC AGENT
- 专利标题（中）： DYSLIPIDEMIA治疗剂
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申请号： EP15844904.1申请日： 2015-09-28
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公开(公告)号： EP3199157A1公开(公告)日： 2017-08-02
- 发明人: INOKUCHI, Yuta , SHIBATA, Haruki , TAKIZAWA, Toshiaki
- 申请人： Kowa Company, Ltd.
- 申请人地址： 6-29, Nishiki 3-chome Naka-ku Nagoya-shi, Aichi 460-8625 JP
- 专利权人： Kowa Company, Ltd.
- 当前专利权人： Kowa Company, Ltd.
- 当前专利权人地址： 6-29, Nishiki 3-chome Naka-ku Nagoya-shi, Aichi 460-8625 JP
- 代理机构： Adam, Holger
- 优先权： JP2014196001 20140926
- 国际公布： WO2016047799 20160331
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/423 ; A61P3/06 ; A61P9/10
摘要：
This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as hyper-LDL cholesterolemia in mammals, including humans.
This invention pertains to a drug composition for preventing and/or treating dyslipidemia and the like, said drug composition comprising the following: (R)-2-[3-[[N-(benzoxazole-2-yl)-N-3-(4-methoxyphenoxy)propy 1]aminomethyl]phenoxyl butyric acid, a salt thereof, or a solvate of either; and (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethy 1}{5-[2-(methylsulfonyl)ethoxy]pyrimidine-2-yl}amino)methyl ]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl} butyric acid, a salt thereof, or a solvate of either.
This invention pertains to a drug composition for preventing and/or treating dyslipidemia and the like, said drug composition comprising the following: (R)-2-[3-[[N-(benzoxazole-2-yl)-N-3-(4-methoxyphenoxy)propy 1]aminomethyl]phenoxyl butyric acid, a salt thereof, or a solvate of either; and (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethy 1}{5-[2-(methylsulfonyl)ethoxy]pyrimidine-2-yl}amino)methyl ]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl} butyric acid, a salt thereof, or a solvate of either.
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