发明公开
EP3199173A1 D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES
审中-公开
D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2用于预防和治疗烧伤
- 专利标题: D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES
- 专利标题(中): D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2用于预防和治疗烧伤
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申请号: EP16188118.0申请日: 2010-03-19
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公开(公告)号: EP3199173A1公开(公告)日: 2017-08-02
- 发明人: TOMPKINS, Ronald G , TZIKA, A Aria , RAHME, Laurence , YU, Yong-Ming , MARTYN, Jeevendra A
- 申请人: The General Hospital Corporation d/b/a Massachusetts General Hospital
- 申请人地址: 55 Fruit Street Boston, MA 02114 US
- 专利权人: The General Hospital Corporation d/b/a Massachusetts General Hospital
- 当前专利权人: The General Hospital Corporation d/b/a Massachusetts General Hospital
- 当前专利权人地址: 55 Fruit Street Boston, MA 02114 US
- 代理机构: Lawrence, John
- 优先权: US162060P 20090320; US249658P 20091008; US258533P 20091105; US259349P 20091109
- 主分类号: A61K38/07
- IPC分类号: A61K38/07 ; A61P17/02
摘要:
The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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