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    D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES
    2.
    发明公开
    D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES 审中-公开
    D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2用于预防和治疗烧伤

    公开(公告)号：EP3199173A1

    公开(公告)日：2017-08-02

    申请号：EP16188118.0

    申请日：2010-03-19

    申请人： The General Hospital Corporation d/b/a Massachusetts General Hospital

    发明人： TOMPKINS, Ronald G ,  TZIKA, A Aria ,  RAHME, Laurence ,  YU, Yong-Ming ,  MARTYN, Jeevendra A

    IPC分类号： A61K38/07 ,  A61P17/02

    CPC分类号： A61K38/07 ,  A61K9/0014 ,  A61K9/0019

    摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.

    摘要翻译： 本公开涉及通过向受试者施用有效量的芳香族阳离子肽来治疗患有烧伤或相关并发症的受试者的方法。 例如，烧伤可能与远处的病理生理效应有关，如高代谢，骨骼肌功能障碍和器官损伤。 本公开还涉及通过将有效量的芳香族阳离子肽给予处于灼伤风险中的受试者而保护受试者免于灼伤。