发明授权
- 专利标题: A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MULTI-DRUG RESISTANT INFECTIONS
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申请号: EP15807704.0申请日: 2015-10-21
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公开(公告)号: EP3212235B1公开(公告)日: 2018-11-28
- 发明人: VISHWAKARMA, Ram , KUMAR, Ajay , KHAN, Inshad Ali , BHARATE, Sandip Bibishan , JOSHI, Prashant , SINGH, Samsher , SATTI, Naresh
- 申请人: Council of Scientific and Industrial Research
- 申请人地址: Anusandhan Bhawan Rafi Marg New Delhi, Maharashtra 110001 IN
- 专利权人: Council of Scientific and Industrial Research
- 当前专利权人: Council of Scientific and Industrial Research
- 当前专利权人地址: Anusandhan Bhawan Rafi Marg New Delhi, Maharashtra 110001 IN
- 代理机构: Carpmaels & Ransford LLP
- 优先权: IN3077DE2014 20141029
- 国际公布: WO2016067309 20160506
- 主分类号: A61K45/06
- IPC分类号: A61K45/06 ; A61K31/351 ; A61K31/352 ; A61K31/496 ; A61K31/7048 ; A61P31/04
摘要:
The bio-efficacy of anti-infective drugs can be potentiated, when used in combination with boeravinone B. Boeravinone B can overcome the resistance or multi-drug resistance developed by bacteria against quinolone, mupirocin and macrolide class of anti-bacterial agents via inhibition of bacterial efflux pumps. Thus, the compositions can be used to treat or prevent drug-resistant bacterial diseases.
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