- 专利标题: PROCESS FOR MAKING ISOQUINOLINE COMPOUNDS
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申请号: EP17155678.0申请日: 2013-07-15
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公开(公告)号: EP3219706A1公开(公告)日: 2017-09-20
- 发明人: THOMPSON, Michael D. , PARK, Jung Min , AREND, Michael P.
- 申请人: Fibrogen, Inc.
- 申请人地址: 409 Illinois Street San Francisco, CA 94158 US
- 专利权人: Fibrogen, Inc.
- 当前专利权人: Fibrogen, Inc.
- 当前专利权人地址: 409 Illinois Street San Francisco, CA 94158 US
- 代理机构: Carpmaels & Ransford LLP
- 优先权: US201261672191P 20120716
- 主分类号: C07D217/26
- IPC分类号: C07D217/26
摘要:
The present invention relates to methods for making isoquinoline compounds and the intermediate compounds achieved thereby. Such compounds can be used to prepare compounds and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
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