发明公开
EP3227279A1 1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS
审中-公开
1-氧代-1,2-二氢异喹啉-7-基 - （5-取代噻吩-2-基） - 磺酰胺化合物，含有这些化合物的制剂及其作为癌症抑制剂用于治疗癌症的用途
- 专利标题： 1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS
- 专利标题（中）： 1-氧代-1,2-二氢异喹啉-7-基 - （5-取代噻吩-2-基） - 磺酰胺化合物，含有这些化合物的制剂及其作为癌症抑制剂用于治疗癌症的用途
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申请号： EP15805705.9申请日： 2015-11-24
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公开(公告)号： EP3227279A1公开(公告)日： 2017-10-11
- 发明人: BROOKS, Harold Burns , DALLY, Robert Dean , DURHAM, Timothy Barrett , FALES, Kevin Robert , FRIMPONG, Kwame , MCCOWAN, Jefferson Ray , NJOROGE, Frank George , SHEPHERD, Timothy Alan , SI, Chong , THRASHER, Kenneth Jeff , TOTH, James Lee , WU, Zhipei
- 申请人： Eli Lilly and Company
- 申请人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 代理机构： Smith, Andrew George
- 优先权： US201462086357P 20141202
- 国际公布： WO2016089670 20160609
- 主分类号： C07D409/12
- IPC分类号： C07D409/12 ; A61K31/4725 ; C07D409/14 ; A61P35/00
摘要：
1-Oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as AICARFT inhibitors.
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