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公开(公告)号:EP3227279B1
公开(公告)日:2019-02-13
申请号:EP15805705.9
申请日:2015-11-24
发明人: BROOKS, Harold Burns , DALLY, Robert Dean , DURHAM, Timothy Barrett , FALES, Kevin Robert , FRIMPONG, Kwame , MCCOWAN, Jefferson Ray , NJOROGE, Frank George , SHEPHERD, Timothy Alan , SI, Chong , THRASHER, Kenneth Jeff , TOTH, James Lee , WU, Zhipei
IPC分类号: C07D409/12 , A61K31/4725 , C07D409/14 , A61P35/00
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2.1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS 审中-公开
标题翻译: 1-氧代-1,2-二氢异喹啉-7-基 - (5-取代噻吩-2-基) - 磺酰胺化合物,含有这些化合物的制剂及其作为癌症抑制剂用于治疗癌症的用途公开(公告)号:EP3227279A1
公开(公告)日:2017-10-11
申请号:EP15805705.9
申请日:2015-11-24
发明人: BROOKS, Harold Burns , DALLY, Robert Dean , DURHAM, Timothy Barrett , FALES, Kevin Robert , FRIMPONG, Kwame , MCCOWAN, Jefferson Ray , NJOROGE, Frank George , SHEPHERD, Timothy Alan , SI, Chong , THRASHER, Kenneth Jeff , TOTH, James Lee , WU, Zhipei
IPC分类号: C07D409/12 , A61K31/4725 , C07D409/14 , A61P35/00
CPC分类号: C07D409/14 , C07C211/07 , C07D409/12
摘要: 1-Oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as AICARFT inhibitors.
摘要翻译: 1-氧代-1,2-二氢异喹啉-7-基 - (5-取代 - 噻吩-2-基) - 磺酰胺化合物,含有这些化合物的制剂,以及它们作为AICARFT抑制剂的用途。
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