发明公开
- 专利标题: QUENCHER
- 专利标题(中): 骤冷
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申请号: EP15870088.0申请日: 2015-12-18
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公开(公告)号: EP3235876A1公开(公告)日: 2017-10-25
- 发明人: SUZUKI Katsufumi , TSURUMI Yoshihisa , KAWANO Kei , IMAZEKI Shigeaki , MURASE Tetsuji
- 申请人: Wako Pure Chemical Industries, Ltd.
- 申请人地址: 1-2, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 540-8605 JP
- 专利权人: Wako Pure Chemical Industries, Ltd.
- 当前专利权人: Wako Pure Chemical Industries, Ltd.
- 当前专利权人地址: 1-2, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 540-8605 JP
- 代理机构: Hinkelmann, Klaus
- 优先权: JP2014256082 20141218; JP2015013679 20150127
- 国际公布: WO2016098889 20160623
- 主分类号: C09B11/28
- IPC分类号: C09B11/28 ; C07D311/78 ; C07D311/82 ; C07D491/16 ; C07D493/10 ; C08F20/30 ; G02B5/20
摘要:
Conventional quenchers do not have quenching ability enough to suppress fluorescence emission of compounds having fluorescent property. Accordingly, it is an object of the present invention to provide a quencher capable of sufficiently quenching fluorescence of the compound having fluorescent property, including a xanthene-based dye.
The present invention relates to a quencher, or the like, comprising a compound represented by the following general formula (1):
[wherein R 5 each independently represent a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an amino group having a substituent or not having a substituent, a hydroxy group, an aryl group, an aryloxy group, or an arylalkyl group; R 6 represents a group having a polymerizable unsaturated group, a hydroxy group, or the like; Y 1 represents an oxygen atom, or the like; An - represents an anion; Ar 1 represents a specific ring structure; * and ** represent binding positions; Ar 2 represents a benzene ring, a naphthalene ring, or an anthracene ring; n 1 represents a specific integer;
and the following structure (1-10) in the general formula (1) is an asymmetric structure;
(wherein R 5 , Y 1 , Ar 1 , Ar 2 , n 1 , * and ** are the same as described above.).].
The present invention relates to a quencher, or the like, comprising a compound represented by the following general formula (1):
[wherein R 5 each independently represent a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an amino group having a substituent or not having a substituent, a hydroxy group, an aryl group, an aryloxy group, or an arylalkyl group; R 6 represents a group having a polymerizable unsaturated group, a hydroxy group, or the like; Y 1 represents an oxygen atom, or the like; An - represents an anion; Ar 1 represents a specific ring structure; * and ** represent binding positions; Ar 2 represents a benzene ring, a naphthalene ring, or an anthracene ring; n 1 represents a specific integer;
and the following structure (1-10) in the general formula (1) is an asymmetric structure;
(wherein R 5 , Y 1 , Ar 1 , Ar 2 , n 1 , * and ** are the same as described above.).].
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