发明公开
EP3269736A1 CONFORMATIONAL-SPECIFIC ANTIBODIES AGAINST OLIGOMERS OF AMYLOID BETA
审中-公开
构象特异性抗体对抗淀粉样β蛋白的寡核苷酸
- 专利标题: CONFORMATIONAL-SPECIFIC ANTIBODIES AGAINST OLIGOMERS OF AMYLOID BETA
- 专利标题(中): 构象特异性抗体对抗淀粉样β蛋白的寡核苷酸
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申请号: EP17185247.8申请日: 2013-05-08
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公开(公告)号: EP3269736A1公开(公告)日: 2018-01-17
- 发明人: Bayer, Thomas
- 申请人: Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin
- 申请人地址: Robert-Koch-Strasse 40 37075 Göttingen DE
- 专利权人: Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin
- 当前专利权人: Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin
- 当前专利权人地址: Robert-Koch-Strasse 40 37075 Göttingen DE
- 代理机构: Wichmann, Hendrik
- 优先权: EP12167565 20120510
- 主分类号: C07K16/18
- IPC分类号: C07K16/18 ; G01N33/68
摘要:
The present invention relates to a conformational specific antibody molecule recognizing a conformational epitope of human trimeric or tetrameric Aβ oligomers, wherein said antibody molecule does not bind human monomeric Aβ 1-42 or human Aβ 1-42 dimers; and pharmaceutical and diagnostic compositions comprising said antibody molecule as well as methods using same.
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