发明公开
EP3269819A1 MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE AND THE METHOD OF PRODUCING O-ACETYL-HOMOSERINE USING THE MICROORGANISM
审中-公开
微生物生产O-乙酰 - 高丝氨酸及使用微生物生产O-乙酰 - 高丝氨酸的方法
- 专利标题： MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE AND THE METHOD OF PRODUCING O-ACETYL-HOMOSERINE USING THE MICROORGANISM
- 专利标题（中）： 微生物生产O-乙酰 - 高丝氨酸及使用微生物生产O-乙酰 - 高丝氨酸的方法
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申请号： EP17187852.3申请日： 2010-03-11
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公开(公告)号： EP3269819A1公开(公告)日： 2018-01-17
- 发明人: Kim, So Young , Shin, Yong Uk , Heo, In Kyung , Kim, Hyun Ah , Seo, Chang Il , Kim, Ju Eun , Son, Sung Kwang , Lee, Sang Mok , Jhon, Sung Hoo , Lee, Han Jin , Na, Kwang Ho
- 申请人： CJ CheilJedang Corporation
- 申请人地址： CJ Bldg. 500 Namdaemunno 5-ga Jung-gu Seoul 100-749 KR
- 专利权人： CJ CheilJedang Corporation
- 当前专利权人： CJ CheilJedang Corporation
- 当前专利权人地址： CJ Bldg. 500 Namdaemunno 5-ga Jung-gu Seoul 100-749 KR
- 代理机构： Leonard, Thomas Charles
- 优先权： US550099 20090828
- 主分类号： C12P13/12
- IPC分类号： C12P13/12 ; C12R1/19
摘要：
Disclosed herein are a microorganism strain capable of producing the L-methionine precursor 0-acetyl homoserine in high yield and a method of producing 0-acetyl homoserine using the same. The microorganism strain is a strain of Escherichia sp. in which an acetyl-CoA synthase gene ( acs ) and/or a pantothenate kinase gene ( coaA ) encoding a pantothenate kinase gene refractory to feedback inhibition by CoA is introduced and expressed.
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