发明公开
EP3273961A1 SOLVATED FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR 审中-公开
溶解形式的突触酪氨酸激酶抑制剂

SOLVATED FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR
摘要:
Described herein are solvates of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the solvates, as well as methods of using the solvates, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
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