发明公开
EP3274471A1 POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY
审中-公开
用于单分子电子SNP测定的聚合物标记的核苷酸
- 专利标题: POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY
- 专利标题(中): 用于单分子电子SNP测定的聚合物标记的核苷酸
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申请号: EP16769553.5申请日: 2016-03-22
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公开(公告)号: EP3274471A1公开(公告)日: 2018-01-31
- 发明人: JU, Jingyue , CHO, Youngjin , KUMAR, Shiv , KALACHIKOV, Sergey , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J.
- 申请人: The Trustees of Columbia University in the City of New York
- 申请人地址: 412 Low Memorial Library 535 West 116th Street New York, New York 10027 US
- 专利权人: The Trustees of Columbia University in the City of New York
- 当前专利权人: The Trustees of Columbia University in the City of New York
- 当前专利权人地址: 412 Low Memorial Library 535 West 116th Street New York, New York 10027 US
- 代理机构: Pernot, Pierre
- 优先权: US201562137014P 20150323
- 国际公布: WO2016154215 20160929
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N15/00 ; G01N33/487
摘要:
This invention provides methods of using labeled nucleotide polyphosphate analogues to detect the identity or presence of a nucleotide at certain positions in nucleic acid sequences with single molecule sensitivity using nanopore detection, nucleotides and primer-conjugated nanopore proteins for use in such methods, and processes for producing such nucleotides and primer-conjugated nanopore proteins.
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