公开(公告)号：EP3274471A1

公开(公告)日：2018-01-31

申请号：EP16769553.5

申请日：2016-03-22

申请人： The Trustees of Columbia University in the City of New York

发明人： JU, Jingyue ,  CHO, Youngjin ,  KUMAR, Shiv ,  KALACHIKOV, Sergey ,  TAO, Chuanjuan ,  CHIEN, Minchen ,  RUSSO, James, J.

IPC分类号： C12Q1/68 ,  G01N15/00 ,  G01N33/487

摘要： This invention provides methods of using labeled nucleotide polyphosphate analogues to detect the identity or presence of a nucleotide at certain positions in nucleic acid sequences with single molecule sensitivity using nanopore detection, nucleotides and primer-conjugated nanopore proteins for use in such methods, and processes for producing such nucleotides and primer-conjugated nanopore proteins.

公开(公告)号：EP3274471B1

公开(公告)日：2020-05-06

申请号：EP16769553.5

申请日：2016-03-22

申请人： The Trustees of Columbia University in the City of New York

发明人： JU, Jingyue ,  CHO, Youngjin ,  KUMAR, Shiv ,  KALACHIKOV, Sergey ,  TAO, Chuanjuan ,  CHIEN, Minchen ,  RUSSO, James, J.

IPC分类号： C12Q1/6869 ,  C12Q1/6827 ,  G01N33/487 ,  G01N15/00