The present invention relates to a process for the production of a device (1) for dispensing eye drops. The process comprises the steps of: —providing a first container (2) and a second container (3) configured to be engaged in a fluid-tight manner, —providing a spacer (4), —introducing a water-based solution (200) inside the first container (2), —introducing a solution or dispersion comprising a drug inside the second container (3), —arranging the spacer (4) between the first and second containers (2, 3), —engaging in a fluid-tight manner the second container (3) and the first container (2); and —freeze-drying the solution or dispersion comprising the drug.