-
公开(公告)号：EP3723744A2
公开(公告)日：2020-10-21
申请号：EP18825596.2
申请日：2018-12-11
发明人： BRANDOLINI, Laura , CUNHA, Thiago, Mattar , ALLEGRETTI, Marcello , ARAMINI, Andrea , BIANCHINI, Gianluca
IPC分类号： A61K31/165 , A61K31/18 , A61K31/381 , A61K31/40 , A61K31/422 , A61K31/427 , A61K31/431 , A61K31/4406 , A61K31/445 , A61P25/02
-
公开(公告)号：EP3497085B1
公开(公告)日：2020-07-22
申请号：EP17746149.8
申请日：2017-08-07
发明人： DE PIZZOL, Maria , SIRICO, Anna , ZIPPOLI, Mara , BIANCHINI, Gianluca , BECCARI, Andrea , ARAMINI, Andrea , LIBERATI, Chiara Rossana Maria
IPC分类号： C07D231/42 , C07D285/04 , C07C311/16 , C07D285/135 , C07C311/21 , C07D263/50 , C07C311/51 , A61P3/00
-
公开(公告)号：EP3518898A1
公开(公告)日：2019-08-07
申请号：EP17859008.9
申请日：2017-10-03
-
公开(公告)号：EP3498269A1
公开(公告)日：2019-06-19
申请号：EP17206813.2
申请日：2017-12-12
发明人： BRANDOLINI, Laura , CUNHA, Thiago Mattar , ALLEGRETTI, Marcello , ARAMINI, Andrea , BIANCHINI, Gianluca
IPC分类号： A61K31/165 , A61K31/18 , A61K31/381 , A61K31/40 , A61K31/422 , A61K31/427 , A61K31/431 , A61K31/4406 , A61K31/445 , A61P25/02
摘要： The present invention relates to C5aR inhibitor compounds, preferably C5aR noncompetitive allosteric inhibitors, useful in the treatment and/or prevention of chemotherapy-induced iatrogenic pain (CIIP).
-
公开(公告)号：EP3497085A1
公开(公告)日：2019-06-19
申请号：EP17746149.8
申请日：2017-08-07
发明人： DE PIZZOL, Maria , SIRICO, Anna , ZIPPOLI, Mara , BIANCHINI, Gianluca , BECCARI, Andrea , ARAMINI, Andrea , LIBERATI, Chiara Rossana Maria
IPC分类号： C07D231/42 , C07D285/04 , C07C311/16 , C07D285/135 , C07C311/21 , C07D263/50 , C07C311/51 , A61P3/00
摘要： The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I): Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GPR40 such as diabetes (particularly type 2 diabetes), impaired oral glucose tolerance, insulin resistance, obesity, obesity related disorders, metabolic syndrome, dyslipidemia, elevated LDL, elevated triglycerides, obesity induced inflammation, osteoporosis and obesity related cardiovascular disorders.
-
公开(公告)号：EP3157918B1
公开(公告)日：2019-03-27
申请号：EP15730801.6
申请日：2015-06-23
发明人： ARAMINI, Andrea , BIANCHINI, Gianluca , BRANDOLINI, Laura , BECCARI, Andrea , LILLINI, Samuele , NANO, Giuseppe
IPC分类号： C07D417/04 , C07D263/42 , A61K31/426 , A61P29/00
-
7.发明公开
公开(公告)号：EP3409277A1
公开(公告)日：2018-12-05
申请号：EP17173515.2
申请日：2017-05-30
IPC分类号： A61K31/427 , A61P31/04
CPC分类号： A61K31/427
摘要： The present invention relates to IL-8 inhibitor compounds, preferably dual CXCR1/CXCR2 receptor inhibitors, useful in the treatment and/or prevention of secondary bacterial infections, preferably secondary respiratory infections.
-
公开(公告)号：EP3280654A1
公开(公告)日：2018-02-14
申请号：EP16725222.0
申请日：2016-04-07
发明人： GENTILE, Marco Maria
CPC分类号： B65D47/18 , A61F9/0008 , B65D81/3211 , F26B5/065 , F26B25/063
摘要： The present invention relates to a process for the production of a device (1) for dispensing eye drops. The process comprises the steps of: —providing a first container (2) and a second container (3) configured to be engaged in a fluid-tight manner, —providing a spacer (4), —introducing a water-based solution (200) inside the first container (2), —introducing a solution or dispersion comprising a drug inside the second container (3), —arranging the spacer (4) between the first and second containers (2, 3), —engaging in a fluid-tight manner the second container (3) and the first container (2); and —freeze-drying the solution or dispersion comprising the drug.
-
公开(公告)号：EP3280377A1
公开(公告)日：2018-02-14
申请号：EP16719520.5
申请日：2016-04-07
发明人： GENTILE, Marco Maria
CPC分类号： A61F9/0008 , A61J1/1406 , A61J1/2089 , B65D47/18 , B65D81/3211
摘要： The present invention relates to a device (1) for dispensing eye drops comprising a first container (2) containing water for injection (200) and a second container (3) containing a freeze-dried composition (300) comprising a drug. The first container (2) comprises a tubular element (9) with an open end portion (10) and the second container (3) comprises a wall (16) configured to be engaged in a fluid-tight manner around the tubular element (9) and a piercible barrier (17) which, in the assembled condition of the device (1), prevents mixing of the substances contained inside the first and second containers (2, 3). The drop dispensing device (1) also comprises a spacer (4) arranged between the first and second containers (2, 3); the spacer (4) does not allow the tubular element (9) to pierce the piercible barrier (17).
-
公开(公告)号：EP2668160B1
公开(公告)日：2015-08-12
申请号：EP12705078.9
申请日：2012-01-27
发明人： MORICONI, Alessio , BIANCHINI, Gianluca , BRANDOLINI, Laura , ARAMINI, Andrea , LIBERATI, Chiara , BOVOLENTA, Silvia , BECCARI, Andrea , LORENZI, Simone
IPC分类号： C07D213/36 , C07D307/52 , C07D307/56 , C07D333/20 , C07D333/28 , C07D207/323 , A61K31/341 , A61K31/381 , A61K31/4025 , A61K31/4402 , A61P29/00
CPC分类号： C07D213/38 , C07D207/323 , C07D207/335 , C07D213/36 , C07D307/52 , C07D307/56 , C07D333/20 , C07D333/28
-
-
-
-
-
-
-
-
-
搜索结果
44 条记录 (耗时 0.022 秒)
