发明公开
EP3283521A1 DRUG CONJUGATES COMPRISING ANTIBODIES AGAINST CLAUDIN 18.2
审中-公开
包含抗CLAUDIN 18.2的抗体的药物缀合物
- 专利标题： DRUG CONJUGATES COMPRISING ANTIBODIES AGAINST CLAUDIN 18.2
- 专利标题（中）： 包含抗CLAUDIN 18.2的抗体的药物缀合物
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申请号： EP16715583.7申请日： 2016-04-13
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公开(公告)号： EP3283521A1公开(公告)日： 2018-02-21
- 发明人: SAHIN, Ugur , TÜRECI, Özlem , WALTER, Korden , KREUZBERG, Maria , MITNACHT-KRAUS, Rita , LE GALL, Fabrice , JACOBS, Stefan
- 申请人： Ganymed Pharmaceuticals GmbH , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址： An der Goldgrube 12 55131 Mainz DE
- 专利权人： Ganymed Pharmaceuticals GmbH,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人： Ganymed Pharmaceuticals GmbH,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人地址： An der Goldgrube 12 55131 Mainz DE
- 代理机构： Schnappauf, Georg
- 优先权： PCT/EP2015/058206 20150415
- 国际公布： WO2016166122 20161020
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/30 ; A61K47/48 ; A61P35/00
摘要：
The present invention provides anti-CLDN18.2 antibody-drug conjugates which are effective for treating and/or preventing cancer diseases associated with cells expressing CLDN18.2, including gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.
公开/授权文献
- EP3283521B1 DRUG CONJUGATES COMPRISING ANTIBODIES AGAINST CLAUDIN 18.2 公开/授权日：2023-11-15
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