- 专利标题： COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
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申请号： EP17175148.0申请日： 2013-04-10
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公开(公告)号： EP3284824A1公开(公告)日： 2018-02-21
- 发明人: BETTENCOURT, Brian , FITZGERALD, Kevin , QUERBES, William , YASUDA, Makiko , DESNICK, Robert J.
- 申请人： Alnylam Pharmaceuticals, Inc. , Icahn School of Medicine at Mount Sinai
- 申请人地址： 300 Third Street Cambridge, MA 02142 US
- 专利权人： Alnylam Pharmaceuticals, Inc.,Icahn School of Medicine at Mount Sinai
- 当前专利权人： Alnylam Pharmaceuticals, Inc.,Icahn School of Medicine at Mount Sinai
- 当前专利权人地址： 300 Third Street Cambridge, MA 02142 US
- 代理机构： Vossius & Partner Patentanwälte Rechtsanwälte mbB
- 优先权： US201261622288P 20120410; US201313835613 20130315
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/713
摘要：
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1.
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