发明公开
EP3316883A1 INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE
审中-公开
来自高通量药物筛选的FKBP51蛋白的抑制剂及使用方法
- 专利标题： INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE
- 专利标题（中）： 来自高通量药物筛选的FKBP51蛋白的抑制剂及使用方法
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申请号： EP15897348.7申请日： 2015-06-30
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公开(公告)号： EP3316883A1公开(公告)日： 2018-05-09
- 发明人: SABBAGH, Jonathan Jacob , DICKEY, Chad
- 申请人： University of South Florida
- 申请人地址： 3802 Spectrum Blvd., Suite 100 Tampa, FL 33612-9220 US
- 专利权人： University of South Florida
- 当前专利权人： University of South Florida
- 当前专利权人地址： 3802 Spectrum Blvd., Suite 100 Tampa, FL 33612-9220 US
- 代理机构： Roberts, Michael Austin
- 国际公布： WO2017003469 20170105
- 主分类号： A61K31/439
- IPC分类号： A61K31/439 ; A61K31/415 ; A61K31/445 ; A61K31/498 ; A61P25/28 ; A61P25/00
摘要：
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
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