专利检索 ap:("University of South Florida") AND inv:"DICKEY, Chad" 第 1 页

1.

发明公开
INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE 审中-公开
标题翻译：来自高通量药物筛选的FKBP51蛋白的抑制剂及使用方法

公开(公告)号：EP3316883A1

公开(公告)日：2018-05-09

申请号：EP15897348.7

申请日：2015-06-30

申请人： University of South Florida

发明人： SABBAGH, Jonathan Jacob , DICKEY, Chad

IPC分类号： A61K31/439 , A61K31/415 , A61K31/445 , A61K31/498 , A61P25/28 , A61P25/00

CPC分类号： A61K31/5415 , A61K31/4168 , A61K31/454 , A61K31/46 , A61K45/06 , A61K2300/00

摘要： The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.