发明公开
- 专利标题： LIGANDS SELECTIVE TO ALPHA 6 SUBUNIT-CONTAINING GABAa RECEPTORS ANS THEIR METHODS OF USE
-
申请号： EP16804541.7申请日： 2016-06-03
-
公开(公告)号： EP3325479A1公开(公告)日： 2018-05-30
- 发明人: CHIOU, Lih-Chu , COOK, James , ERNST, Margot , FAN, Pi-Chuan , KNUTSON, Daniel , MEIRELLES, Matheus , MIHOVILOVIC, Marko , SIEGHART, Werner , VARAGIC, Zdravko , VERMA, Ranjit , WIMMER, Laurin , WITZIGMANN, Christopher , SIEBERT, David, Chan Bodin , SAVIC, Miroslav, M.
- 申请人： UWM Research Foundation, Inc. , Medical University Of Vienna , National Taiwan University , University of Belgrade-Faculty of Pharmacy
- 申请人地址： 1440 East North Avenue Milwaukee, WI 53202 US
- 专利权人： UWM Research Foundation, Inc.,Medical University Of Vienna,National Taiwan University,University of Belgrade-Faculty of Pharmacy
- 当前专利权人： UWM Research Foundation, Inc.,Medical University Of Vienna,National Taiwan University,University of Belgrade-Faculty of Pharmacy
- 当前专利权人地址： 1440 East North Avenue Milwaukee, WI 53202 US
- 代理机构： Stafford, Jonathan Alan Lewis
- 优先权： US201562170552P 20150603; US201662307836P 20160314
- 国际公布： WO2016196961 20161208
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D471/14 ; C07D401/04 ; C07D403/04 ; A61K31/437 ; A61K31/4375 ; A61K31/4439
摘要：
Provided herein are novel pyrazolo-quinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis;depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.
公开/授权文献
信息查询
