- 专利标题: COMPOUND FOR IN VIVO DIAGNOSIS OF A DYSFUNCTION OF ADRENAL GLANDS
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申请号: EP17154441.4申请日: 2017-02-02
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公开(公告)号: EP3357910A1公开(公告)日: 2018-08-08
- 发明人: Schirbel, Andreas , Heinze, Britta , Hahner, Stefanie
- 申请人: Julius-Maximilians-Universität Würzburg
- 申请人地址: Sanderring 2 97070 Würzburg DE
- 专利权人: Julius-Maximilians-Universität Würzburg
- 当前专利权人: Julius-Maximilians-Universität Würzburg
- 当前专利权人地址: Sanderring 2 97070 Würzburg DE
- 代理机构: Dr. Gassner & Partner mbB
- 主分类号: C07D213/73
- IPC分类号: C07D213/73 ; A61K51/04 ; C07D213/74 ; C07D213/82 ; C07D213/84 ; C07D217/14 ; C07D405/04 ; C07D241/12 ; C07D241/16 ; C07D241/18 ; C07D241/20 ; C07D241/24 ; C07D213/57 ; C07D213/61 ; C07D213/65 ; C07D213/70 ; A61K31/44 ; A61K31/47 ; A61K31/4965
摘要:
The invention concerns a compound having formula (I):
wherein R1 represents a radioactive isotope of an element which radioactive isotope is detectable by positron emission tomography (PET) or wherein R1 represents any nonradioactive isotope of said element, R2 represents -CN or -CF 3 , wherein R3 represents
wherein * represents C or N and R4 represents one of the moieties of a group consisting of alkyl, alkyl ether, alkyl nitrile, alkyl alcohol, alkyl halide, O-alkyl, S-alkyl, halogen, nitrile, trifluoromethyl, amino, aminoalkyl, aminodialkyl, phenyl, substituted phenyl, heterocyclic aromatic or a substituted heterocyclic aromatic, dioxolanyl, methyldioxolanyl, and dioxanyl.
wherein R1 represents a radioactive isotope of an element which radioactive isotope is detectable by positron emission tomography (PET) or wherein R1 represents any nonradioactive isotope of said element, R2 represents -CN or -CF 3 , wherein R3 represents
wherein * represents C or N and R4 represents one of the moieties of a group consisting of alkyl, alkyl ether, alkyl nitrile, alkyl alcohol, alkyl halide, O-alkyl, S-alkyl, halogen, nitrile, trifluoromethyl, amino, aminoalkyl, aminodialkyl, phenyl, substituted phenyl, heterocyclic aromatic or a substituted heterocyclic aromatic, dioxolanyl, methyldioxolanyl, and dioxanyl.
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