- 专利标题： USE OF SERUM 2-CYSTEINE PEROXIREDOXINS (2-CYS-PRDX) AS BIOMARKERS OF CHRONIC KIDNEY DISEASES (CKD) SUCH AS LUPUS NEPHRITIS (LN), IGA NEPHROPATHY (IGAN) AND AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) USEFUL FOR DIAGNOSING, MONITORING, AND PROGNOSING IN THESE DISEASES AND METHOD OF DIFFERENTIATION OF THESE DISEASES
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申请号： EP17461508.8申请日： 2017-02-04
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公开(公告)号： EP3358355A1公开(公告)日： 2018-08-08
- 发明人: MUCHA, Krzysztof , ZAGOZDZON, Radoslaw , FORONCEWICZ, Bartosz , PACZEK, Leszek , KRATA, Natalia , GALA, Kamila
- 申请人： Warszawski Uniwersytet Medyczny
- 申请人地址： Ul. Zwirki i Wigury 61 02-091 Warszawa PL
- 专利权人： Warszawski Uniwersytet Medyczny
- 当前专利权人： Warszawski Uniwersytet Medyczny
- 当前专利权人地址： Ul. Zwirki i Wigury 61 02-091 Warszawa PL
- 代理机构： Patpol Kancelaria Patentowa Sp. z o.o.
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; G01N33/564
摘要：
The resent invention relates to the use of at least one of 2-Cys-PRDXs selected from a group consisting of PRDX1, PRDX2, PRDX3, PRDX4 and PRDX5 as a biomarker to diagnose, differentiate and/or assess the risk of chronic kidney disease (CDK). Present invention also relates to the method of diagnosis and the method of determining an increased risk of chronic kidney disease (CKD). Present invention also provides a kit suitable for diagnosis and differentiation of chronic kidney disease (CKD) selected from the group comprising lupus nephritis (LN), IgA nephropathy (IgAN) and autosomal-dominant polycystic kidney disease (ADPKD) in a subject.
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