- 专利标题: 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS
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申请号: EP16784732.6申请日: 2016-10-13
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公开(公告)号: EP3362442A1公开(公告)日: 2018-08-22
- 发明人: KIM, Soong-Hoon , CHAO, Hannguang J. , FINLAY, Heather , JIANG, Ji , JOHNSON, James A. , LAWRENCE, R. Michael , MYERS, Michael C. , PHILLIPS, Monique , TORA, George O. , MENG, Wei
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: Route 206 and Province Line Road Princeton, NJ 08543 US
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: Route 206 and Province Line Road Princeton, NJ 08543 US
- 代理机构: Kling, Edouard
- 优先权: US201562241367P 20151014; US201562270659P 20151222
- 国际公布: WO2017066402 20170420
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D213/82 ; C07D401/06 ; C07D401/12 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07D471/10 ; C07D491/107 ; C07D498/10 ; A61K31/4427 ; A61P9/00
摘要:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
公开/授权文献
- EP3362442B1 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS 公开/授权日:2020-01-29
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