- 专利标题： CRYSTALLINE FORMS OF BEDAQUILINE FUMARATE AND PREPARATION METHODS THEREFOR
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申请号： EP15906444.3申请日： 2015-10-20
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公开(公告)号： EP3366676A1公开(公告)日： 2018-08-29
- 发明人: XU, Jinyi , ZHANG, Liang , ZHANG, Xiangyang , WANG, Xinzeng , CHAI, Jian , LUO, Hongying , YANG, Zhiqing
- 申请人： Zhejiang Hisun Pharmaceutical Co., Ltd
- 申请人地址： No. 46 Waisha Road Jiaojiang District Taizhou Zhejiang 318000 CN
- 专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd
- 当前专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd
- 当前专利权人地址： No. 46 Waisha Road Jiaojiang District Taizhou Zhejiang 318000 CN
- 代理机构： Kador & Partner PartG mbB
- 国际公布： WO2017066926 20170427
- 主分类号： C07D215/227
- IPC分类号： C07D215/227
摘要：
Provided are crystal forms I, II, and III of bedaquiline fumarate, and preparation methods thereof. The crystal forms have high purity, excellent physicochemical properties, and good stability. The preparation methods can effectively improve the quality of products, and are applicable to preparation and mass production of medicines.
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