公开(公告)号：EP3366676A1

公开(公告)日：2018-08-29

申请号：EP15906444.3

申请日：2015-10-20

申请人： Zhejiang Hisun Pharmaceutical Co., Ltd

发明人： XU, Jinyi ,  ZHANG, Liang ,  ZHANG, Xiangyang ,  WANG, Xinzeng ,  CHAI, Jian ,  LUO, Hongying ,  YANG, Zhiqing

IPC分类号： C07D215/227

CPC分类号： C07D215/227 ,  A61P31/06 ,  B01D9/0063

摘要： Provided are crystal forms I, II, and III of bedaquiline fumarate, and preparation methods thereof. The crystal forms have high purity, excellent physicochemical properties, and good stability. The preparation methods can effectively improve the quality of products, and are applicable to preparation and mass production of medicines.