发明公开
- 专利标题： METHODS FOR TREATING CONDITIONS ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION
-
申请号： EP16864904.4申请日： 2016-11-09
-
公开(公告)号： EP3373963A1公开(公告)日： 2018-09-19
- 发明人: DEMOPULOS, Gregory, A. , DUDLER, Thomas , SCHWAEBLE, Hans-Wilhelm
- 申请人： Omeros Corporation , University of Leicester
- 申请人地址： 201 Elliott Avenue West Seattle, WA 98119 US
- 专利权人： Omeros Corporation,University of Leicester
- 当前专利权人： Omeros Corporation,University of Leicester
- 当前专利权人地址： 201 Elliott Avenue West Seattle, WA 98119 US
- 代理机构： Avidity IP
- 优先权： US201562252814P 20151109; US201662406726P 20161011
- 国际公布： WO2017083371 20170518
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/395 ; A61P7/02 ; A61P37/02 ; C07K16/40
摘要：
In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
信息查询
