- 专利标题： TREATMENT OF AGE-RELATED MACULAR DEGENERATION USING RNA COMPLEXES THAT TARGET MYD88 OR TLR3
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申请号： EP16865834.2申请日： 2016-11-15
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公开(公告)号： EP3377630A1公开(公告)日： 2018-09-26
- 发明人: LEE, Dong-ki , HONG, Sun Woo , HONG, Isu , HWANG, Ji Hye
- 申请人： Olix Pharmaceuticals, Inc.
- 申请人地址： 1014 Gwanggyo Ace Tower1, 17, Daehak 4-ro, Yeongtong-gu Suwon-si, Gyeonggi-do 16226 KR
- 专利权人： Olix Pharmaceuticals, Inc.
- 当前专利权人： Olix Pharmaceuticals, Inc.
- 当前专利权人地址： 1014 Gwanggyo Ace Tower1, 17, Daehak 4-ro, Yeongtong-gu Suwon-si, Gyeonggi-do 16226 KR
- 代理机构： Ladendorf, Oliver
- 优先权： US201562255878P 20151116
- 国际公布： WO2017085550 20170526
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K9/00
摘要：
In certain aspects, provided herein are RNA complexes that inhibit Myeloid differentiation primary response gene 88 (MyD88) and/or Toll-like receptor 3 (TLR3) and are useful in the treatment of age-related macular degeneration (AMD). In certain aspects, provided herein are pharmaceutical compositions comprising such RNA complexes and methods of using such RNA complexes and pharmaceutical compositions.
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