- 专利标题: HEXAHYDROPYRAZINOBENZ- OR -PYRIDO-OXAZEPINES CARRYING AN OXYGEN-CONTAINING SUBSTITUENT AND USE THEREOF IN THE TREATMENT OF 5-HT2C-DEPENDENT DISORDERS
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申请号: EP16804731.4申请日: 2016-11-24
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公开(公告)号: EP3380483A1公开(公告)日: 2018-10-03
- 发明人: BACKFISCH, Gisela , BAKKER, Margaretha Henrica Maria , BLAICH, Günter , BRAJE, Wilfried , DRESCHER, Karla , ERHARD, Thomas , HAUPT, Andreas , HOFT, Carolin , LAKICS, Viktor , MACK, Helmut , OELLIEN, Frank , PETER, Raimund , RELO, Ana Lucia
- 申请人: Abbvie Deutschland GmbH & Co. KG
- 申请人地址: Mainzer Straße 81 65189 Wiesbaden DE
- 专利权人: Abbvie Deutschland GmbH & Co. KG
- 当前专利权人: Abbvie Deutschland GmbH & Co. KG
- 当前专利权人地址: Mainzer Straße 81 65189 Wiesbaden DE
- 代理机构: Bensiek, Stephan
- 优先权: US201562259776P 20151125
- 国际公布: WO2017089458 20170601
- 主分类号: C07D498/04
- IPC分类号: C07D498/04 ; C07D498/14 ; A61K31/553 ; A61P25/24
摘要:
The present invention relates to compound of formula (I) (I) wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT2C receptor, to their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT2C receptor, and to methods for preventing or treating conditions and disorders which respond to the modulation of 5-HT2C receptor.
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