- 专利标题： PEPTIDE COMPOUNDS AND PEPTIDE CONJUGATES FOR THE TREATMENT OF CANCER THROUGH RECEPTOR-MEDIATED CHEMOTHERAPY
-
申请号： EP16867488.5申请日： 2016-11-24
-
公开(公告)号： EP3380495A1公开(公告)日： 2018-10-03
- 发明人: BÉLIVEAU, Richard , ANNABI, Borhane , DEMEULE, Michel , LAROCQUE, Alain , CURRIE, Jean-christophe , CHARFI, Cyndia
- 申请人： Transfert Plus, S.E.C.
- 申请人地址： 355 rue Peel Bureau 503 Montréal, Québec H3C 2G9 CA
- 专利权人： Transfert Plus, S.E.C.
- 当前专利权人： Transfert Plus, S.E.C.
- 当前专利权人地址： 355 rue Peel Bureau 503 Montréal, Québec H3C 2G9 CA
- 代理机构： Regimbeau
- 优先权： US201562259178P 20151124
- 国际公布： WO2017088058 20170601
- 主分类号： C07K14/195
- IPC分类号： C07K14/195 ; A61K47/66 ; A61P35/00 ; C07C43/295 ; C07D305/14 ; C07H15/252 ; C07K1/06 ; C07K1/113 ; C07K14/00 ; C07K14/47 ; C07K17/00 ; C07K7/08 ; C40B40/10 ; A61K9/127
摘要：
The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer and increasing cellular internalization of said peptide compounds. The peptide compounds are selected from the following group consisting of; GVRAKAGVRNMFKSESY as set forth in SEQ ID NO: 9; GVRAKAGVRN(Nle)FKSESY as set forth in SEQ ID NO: 10; and YKSLRRKAPRWDAPLRDPALRQLL as set forth in SEQ ID NO: 11; and wherein at least one protecting group and/or at least one labelling agent is connected to said peptide compound.
公开/授权文献
信息查询
