- 专利标题： METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA)
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申请号： EP16819754.9申请日： 2016-12-01
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公开(公告)号： EP3383376A1公开(公告)日： 2018-10-10
- 发明人: HAZEN, Stanley, Leon , GARCIA-GARCIA, Jose Carlos , GERBERICK, George, Franklin , WOS, John, August , STANTON, David, Thomas , INGLIN, Thomas, Alfred , REILLY, Michael , DEUTSCH, Angela, Jane , REED, Jodie, Michelle , CODY, David, Blair
- 申请人： The Procter & Gamble Company , The Cleveland Clinic Foundation
- 申请人地址： One Procter & Gamble Plaza Cincinnati, OH 45202 US
- 专利权人： The Procter & Gamble Company,The Cleveland Clinic Foundation
- 当前专利权人： The Procter & Gamble Company,The Cleveland Clinic Foundation
- 当前专利权人地址： One Procter & Gamble Plaza Cincinnati, OH 45202 US
- 代理机构： Töpert, Verena Clarita
- 优先权： US201562261645P 20151201; US201562261662P 20151201; US201662356422P 20160629
- 国际公布： WO2017095995 20170608
- 主分类号： A61K31/04
- IPC分类号： A61K31/04 ; A61K31/095 ; A61K31/275 ; A61K31/26
摘要：
The invention also provides for a method of inhibiting the production of TMA by bacteria comprising administering to the individual a composition comprising a compound set forth in FORMULA (I) wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline or carnitine in the individual.
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