发明公开
- 专利标题： METHOD OF PRODUCING PROTEINS IN FILAMENTOUS FUNGI WITH DECREASED CLR2 ACTIVITY
-
申请号： EP16808597.5申请日： 2016-12-02
-
公开(公告)号： EP3384002A1公开(公告)日： 2018-10-10
- 发明人: HAEFNER, Stefan , THYWISSEN, Andreas , HARTMANN, Holger , BOEHMER, Nico
- 申请人： BASF SE
- 申请人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 代理机构： Maiwald Patent- und Rechtsanwaltsgesellschaft mbH
- 优先权： EP15197497 20151202
- 国际公布： WO2017093450 20170608
- 主分类号： C12N1/14
- IPC分类号： C12N1/14 ; C12R1/645 ; C12P21/02
摘要：
The present invention relates to a method of producing a recombinant polypeptide a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 2 (CLR2) and to express said recombinant polypeptide. The method further relates to a filamentous fungus Myceliophthora thermophila, which is genetically modified to decrease or eliminate the activity of CLR2 and the use of this filamentous fungus in the production of a recombinant polypeptide.
信息查询
IPC分类:
