- 专利标题： POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE
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申请号： EP16820106.9申请日： 2016-12-09
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公开(公告)号： EP3386991A1公开(公告)日： 2018-10-17
- 发明人: ARORA, Nidhi , BACANI, Genesis M. , BARBAY, Joseph Kent , BEMBENEK, Scott D. , CAI, Min , CHEN, Wei , DECKHUT, Charlotte Pooley , EDWARDS, James P. , GHOSH, Brahmananda , KREUTTER, Kevin , LI, Gang , TICHENOR, Mark S. , VENABLE, Jennifer D. , WEI, Jianmei , WIENER, John J. M. , WU, Yao , XIAO, Kun , ZHANG, Feihuang , ZHU, Yaoping
- 申请人： Janssen Pharmaceutica NV
- 申请人地址： Turnhoutseweg 30 2340 Beerse BE
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： Turnhoutseweg 30 2340 Beerse BE
- 代理机构： McGuire, Gillian Margaret
- 优先权： US201562265836P 20151210
- 国际公布： WO2017100662 20170615
- 主分类号： C07D495/16
- IPC分类号： C07D495/16 ; C07D519/00 ; A61K31/519 ; A61P35/00 ; A61P37/00 ; A61P19/00
摘要：
The present disclosure is directed to compounds of Formula (I) as Bruton's kinase inhibitors and their preparation, as well as compositions comprising compounds of Formula (I).
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