METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES
摘要:
The invention provides a method comprising: forming an expandable tubular body comprising a plurality of braided filaments, wherein the expandable tubular body is configured to be implanted in a blood vessel, and wherein the plurality of braided filaments comprises a first filament comprising platinum or platinum alloy and a second filament comprising cobalt-chromium alloy; chemically bonding a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament; applying a silane intermediate layer on the second filament comprising the cobalt-chromium alloy; and applying a second phosphorylcholine material on the silane intermediate layer on the second filament, wherein the first and second phosphorylcholine materials each define a respective thickness of less than 100 nanometers.
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