公开(公告)号：EP3400973B1

公开(公告)日：2020-02-12

申请号：EP18179020.5

申请日：2014-11-18

申请人： Covidien LP

发明人： SHEU, Min-Shyan ,  MA, Xiaodong ,  WAINWRIGHT, John ,  ERAMO, Lincoln ,  LI, Junwei

IPC分类号： A61L31/02 ,  A61L31/10 ,  A61L31/16

公开(公告)号：EP3400973A1

公开(公告)日：2018-11-14

申请号：EP18179020.5

申请日：2014-11-18

申请人： Covidien LP

发明人： SHEU, Min-Shyan ,  MA, Xiaodong ,  WAINWRIGHT, John ,  ERAMO, Lincoln ,  LI, Junwei

IPC分类号： A61L31/02 ,  A61L31/10 ,  A61L31/16

摘要： The invention provides a method comprising: forming an expandable tubular body comprising a plurality of braided filaments, wherein the expandable tubular body is configured to be implanted in a blood vessel, and wherein the plurality of braided filaments comprises a first filament comprising platinum or platinum alloy and a second filament comprising cobalt-chromium alloy; chemically bonding a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament; applying a silane intermediate layer on the second filament comprising the cobalt-chromium alloy; and applying a second phosphorylcholine material on the silane intermediate layer on the second filament, wherein the first and second phosphorylcholine materials each define a respective thickness of less than 100 nanometers.