- 专利标题： INDANE DERIVATIVES AS MGLUR7 MODULATORS
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申请号： EP17707970.4申请日： 2017-01-24
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公开(公告)号： EP3408256A1公开(公告)日： 2018-12-05
- 发明人: GOLDBY, Anne , LIWICKI, Gemma , MACK, Stephen , TEALL, Martin , WHITE, Katy
- 申请人： Takeda Pharmaceutical Company Limited
- 申请人地址： 1-1 Doshomachi 4-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： 1-1 Doshomachi 4-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 代理机构： Elend, Almut Susanne
- 优先权： GB201601301 20160125
- 国际公布： WO2017131221 20170803
- 主分类号： C07C233/23
- IPC分类号： C07C233/23 ; C07D309/08 ; C07D309/14 ; C07C271/24 ; C07D231/12 ; C07D231/14 ; C07C311/06 ; C07D237/14 ; C07C317/30 ; C07D239/42 ; C07D413/12 ; C07C233/41 ; C07D261/10 ; C07C235/36 ; C07D205/04
摘要：
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4a and R4b are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of formula (I) are mGluR7 modulators.
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