- 专利标题： TRICYCLIC COMPOUND FOR BROMODOMAIN-CONTAINING PROTEIN INHIBITOR AND PREPARATION, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF
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申请号： EP17747001.0申请日： 2017-02-04
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公开(公告)号： EP3412669A1公开(公告)日： 2018-12-12
- 发明人: LI, Jijun , WU, Wei , ZHU, Yan , WANG, Huting , ZHAO, Lijia , HE, Weinan , SUN, Yinghui , PENG, Yong , HAN, Yongxin
- 申请人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd , Centaurus BioPharma Co., Ltd. , Lianyungang Runzhong Pharmaceutical Co., Ltd.
- 申请人地址： No. 369 Yuzhou South Road Haizhou District Lianyungang, Jiangsu 222062 CN
- 专利权人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd,Centaurus BioPharma Co., Ltd.,Lianyungang Runzhong Pharmaceutical Co., Ltd.
- 当前专利权人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd,Centaurus BioPharma Co., Ltd.,Lianyungang Runzhong Pharmaceutical Co., Ltd.
- 当前专利权人地址： No. 369 Yuzhou South Road Haizhou District Lianyungang, Jiangsu 222062 CN
- 代理机构： Maiwald Patent- und Rechtsanwaltsgesellschaft mbH
- 优先权： CN201610080167 20160205
- 国际公布： WO2017133681 20170810
- 主分类号： C07D471/14
- IPC分类号： C07D471/14 ; C07D471/04 ; A61K31/4375 ; A61K31/437 ; A61P35/00 ; A61P31/12 ; A61P25/28 ; A61P29/00 ; A61P9/10
摘要：
The present applicationpresent application relates to a compound represented by Formula (III) or a pharmaceutically acceptable salt, solvent compound, active metabolite, crystal polymorph, ester, isomer, or prodrug thereof. The application further provides a pharmaceutical composition comprising the compound represented by Formula (III) and a use thereof for preparing a bromodomain inhibitor for preventing or treating various diseases, such as inflammation and cancer, related to the bromodomain.
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