- 专利标题： INDIVIDUALIZED VACCINES FOR CANCER
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申请号： EP18172228.1申请日： 2013-11-26
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公开(公告)号： EP3417874A1公开(公告)日： 2018-12-26
- 发明人: SAHIN, Ugur , PARET, Claudia , VORMBROCK, Kirsten , BENDER, Christian , DIEKMANN, Jan
- 申请人： BioNTech RNA Pharmaceuticals GmbH , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址： An der Goldgrube 12 55131 Mainz DE
- 专利权人： BioNTech RNA Pharmaceuticals GmbH,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人： BioNTech RNA Pharmaceuticals GmbH,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人地址： An der Goldgrube 12 55131 Mainz DE
- 代理机构： Böhmer, Thomas
- 优先权： EP12008007 20121128
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The present invention relates to a patient-specific tumor treatment targeting individual expression patterns of tumor antigens, in particular shared tumor antigens, and individual tumor mutations. In one aspect, the present invention relates to a method for preventing or treating cancer in a patient comprising the steps of: (i) inducing a first immune response against one or more tumor antigens in the patient, and (ii) inducing a second immune response against one or more tumor antigens in the patient wherein the second immune response is specific for cancer specific somatic mutations present in cancer cells of the patient.
公开/授权文献
- EP3417874B1 INDIVIDUALIZED VACCINES FOR CANCER 公开/授权日：2024-09-11
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